Bolivia's largest city and gateway to the surrounding area
Located just beyond the last Andean foothills in the tropical lowlands, is Santa Cruz, Bolivia’s economic powerhouse. What was an isolated frontier town until the middle of the 20th century has now become the country’s biggest city.
Rapid growth has meant residential districts and commercial developments have boomed, but the old colonial city centre is still dominated by cobbled streets and whitewashed houses with pretty tiled roofs. At the heart of the city is the central plaza, Plaza 24 de Septiembre. Its name refers to the date of the uprising that led to Santa Cruz’s independence from Spain. It is a popular meeting point for locals and you’ll find people of all ages drinking, chatting and socialising.
Santa Cruz offers travellers an insight into a more modern Bolivia and with the greatest population diversity in the country, it makes an interesting stopover. And, being such a transport hub, it’s the perfect base for exploring the epic surroundings.
The Jacada Difference
Seamless organisation, every step of the way
Journeys as meaningful as they are memorable
Remarkable stays, handpicked by our experts
Luxury accommodation in Santa Cruz
Why book with Jacada?

Personalised design
We’ll plan your trip around your specific interests, tastes and preferences, providing helpful tips and honest advice based on first-hand knowledge of the destination.

Authentic experiences
Our expert guides and brilliant travel concierges are hand-picked to provide a genuine experience, bringing your destination to life with care and passion.

Responsible travel
Our luxury trips are designed with responsible travel principles that prioritise travel experiences that are both good for you and good for the planet.
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Plan your trip to Santa Cruz
Whatever you want from your adventure in Santa Cruz, our team of expert travel designers are ready to help.


Plan with peace of mind
When you book a trip in today’s world there’s a lot to think about. But with the right advice and expert planning, you can do it with confidence.
If you book to travel with us but your plans are impacted by circumstances you can’t control, we’ll change your reservation or cancel your booking for a full credit towards future travel.